VTE Risk Assessment in Pregnancy (Antenatal)

Preexisting risk factor

• Previous VTE (4)
• High risk thrombophilia (3)
• anti thrombin, protein C, protein S deficiency
• Medical comorbidities (3)
• malignancies
• cardiac failure, active SLE
• IVDU 
• TB
• nephrotic syndrome
• DM with nephropathy
• thalassemia major / intermedia
• post splenectomy
• Obesity
• BMI  ≥ 40kg/m2 (2)
• BMI 30-39 kg/m2 (1)
• Family history of VTE (1)
• Low risk thrombophilia (1)
• Factor V Leiden
• High FVIII
• Current smoker  ≥ 10/day (1)
• Twin / multiple pregnancy (1)

Interpretation of scoring (for antenatal only)

• score  ≥ 4 : consider thromboprophylaxis from 1st trimester until post delivery
• score 3 : consider prophylaxis from 28 weeks until 3 weeks postnatal