Preeclampsia prophylaxis during pregnancy

 Preeclampsia prophylaxis during pregnancy

1. High Risks

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• History of preeclampsia or pregnancy induced hypertension during previous pregnancy

• Chronic hypertension

• Type 1 or type 2 diabetes mellitus

• chronic renal disease

• Autoimmune disease (SLE, Antiphospholipid syndrome)

• Twin / Multiple pregnancy

2. Moderate Risks

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• Primigravida / pseudo-primigravida

• Age ≥ 35 years old

• BMI ≥ 30at booking

• Family history of preeclampsia (mother or sister)

• Long spacing (>10 years)

• IVF pregnancy

3. Interpretation

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• if have 1 high risk or 2 moderate risks, to start PE prophylaxis

4. Preeclampsia prophylaxis medications

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• cardiprin 100mg OD (or aspirin 150mg OD ) 

• start once fetal heart visible or from 12 weeks onward 

• calcium carbonate 1g BD

• start at 20 weeks of gestation

• vitamin D 800-1000 IU OD

• start at 20 weeks of gestation